Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab01379( CCL17 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat heart using FNab01379( CCL17 Antibody) at dilution of 1:50
Background
This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells.